Town slipped to a 3-0 defeat to Millwall in the final home game of the 2011/12 season.
A brace from Andrew Keogh either side of a goal from former Blue Liam Trotter was enough for the Lions, although Grant Leadbitter did see a late penalty saved by Maik Taylor.
Paul Jewell made two changes to the side that drew with Birmingham in the week, with Ryan Stevenson and Jay Emmanuel-Thomas replacing Jason Scotland and Lee Martin.
The Town boss also named 16-year old Byron Lawrence amongst the substitutes.
However it was the visitors who were the quicker out of the blocks and opened the scoring inside the first two minutes.
Good work on the left from Trotter saw him cross into the box for striker Keogh, whose initial shot was blocked by Arran Lee-Barrett, but the ball ricocheted towards goal and over the line despite Aaron Cresswell's best efforts in trying to clear the ball.
Blues did respond to going a goal behind well though, with Andy Drury dragging a shot wide of Taylor's goal following a neat pass from Ryan Stevenson.
On the 15th minute mark Town went close again. A good run and cross from, Daryl Murphy saw him pick out Michael Chopra at the back-post, but the striker could only head into the side-netting from inside the six-yard box.
Midfielder Grant Leadbitter was linking the play well in midfield and was unlucky to see a well-hit drive fly just over Taylor's bar after 25 minutes.
Five minutes later and Town created another good opportunity. Carlos Edwards beat his man before whipping in a teasing cross from the right to pick out Chopra, but the striker headed straight into the grateful arms of Taylor.
Town suffered a small scare on the stroke of half-time, as Lee-Barrett scuffed a kick straight into the path of James Henry, but the winger's effort sailed high over the bar despite the 'keeper being out of his goal.
That proved to be the last action of the half and Town went in a goal behind at the break.
Jason Scotland emerged for the second-half, replacing Stevenson, and the striker was immediately in the thick of the action, teeing up Leadbitter for shot three minutes after the restart that deflected over the bar.
Town were beginning to apply the pressure on the Millwall goal and came close to equalising just before the hour mark.
Good running from Chopra saw him beat the offside trap and head into the box, before pulling the ball back across the face of goal which was then turned onto the post by a Millwall defender. Scotland then picked up the rebound only to see his effort cleared off the line by Tony Craig.
However Town soon found themselves two down as Trotter fired the Lions further ahead after 63 minutes.
Substitute Ibrahima Sonko cleared the first ball but Trotter was the first to react on the edge of the area and planted a shot behind the reach of Lee-Barrett and into the top corner.
Blues did try to find an immediate response, with Emmanuel-Thomas being denied by a smart save from Taylor after 66 minutes.
Scotland was looking a threat for Town and was unfortunate to see his low drive turned behind for a corner by Taylor, with 14 minutes remaining.
Drury was a tireless worker in midfield for Blues and his direct running saw him fouled in the area with seven minutes remaining, with referee Colin Webster having no hesitations in pointing to the spot.
Leadbitter stepped up but saw his spot-kick kept out by Taylor, who dived low to his left to keep his clean sheet intact.
The save gave the visitors extra life into their attack and Keogh wrapped the points up with three minutes remaining, scoring his second of the game after rounding Lee-Barrett before sliding the ball into the empty net.
That was the way it stayed as Town ended their home fixtures on a losing note. Blues complete the season away at Doncaster next weekend, kick-off 12.30pm.
Town: Lee-Barrett, Edwards, Delaney, Smith, Cresswell (Sonko 62), Emmanuel-Thomas, Leadbitter, Drury, Stevenson (Scotland 46), Murphy, Chopra (Carson 69). Subs not used: Bowyer, Lawrence.
Millwall: Taylor, Smith, Robinson, Lowry, Craig, Henry (Feeney 88), Trotter, Abdou, Wright, Kane, Keogh (Batt 90). Subs not used: Forde, Dunne, Barron.
Att: 18, 947 (1, 298 visiting fans)