Town boss Jim Magilton has said Dan Harding is likely to be followed by other Blues going out on loan.
The full-back is joining Reading until the end of the season, with Billy Clarke (Northampton), Richard Naylor (Leeds), Jordan Rhodes (Brentford), Chris Casement (Wycombe), Jaime Peters (Gillingham) and Kurt Robinson (Rushden) also out on loan.
"It's important that we get players out and playing football and we are talking to clubs about taking on some of our other young players here," Jim told the Club website.
"Ed Upson has been spending the week with Southend and we'd like to find him some first-team football and it's the same with Jai Reason.
"Playing reserve team football is of no real use for lads like Ed and Jai now, they need to taking the next step and that means playing in League games week in, week out."
Ed and Jai are both out of contract in the summer.